This course is divided into 3 parts. Each part will include content-based learning in which we examine several aspects of cell biology using lectures, discussion of experimental results and materials from the textbook. Topics will include exocytosis, actin & microtubule cytoskeleton, motors, and mitosis. Each part will also include inquiry-based learning where you will work in groups on a short research project to understand the cellular and molecular basis of a human genetic disease. Each group will investigate 3 aspects of their assigned disease: (1) the cell biology of the organelle or process that is disrupted, (2) the gene product that is defective, and (3) the experimental methods that scientists are using to understand, treat or cure the disease. This inquiry-based learning will culminate in each group presenting their work to the class and writing a short report summarizing their findings.