Computer Science 690R - Computing/DigiBiomarkersinHC

Computer science has played a pivotal role in developing innovative technologies to monitor patients' health conditions beyond the traditional laboratory or clinical environments. The development of clinically valid digital biomarkers can enable a wide range of applications, including the implementation of targeted behavioral interventions to drive substantial improvements in health-related outcomes, monitoring the progress of individuals undergoing interventions, and assessing the efficacy of emerging therapeutic interventions as an endpoint. In this course, we will delve into the application of machine learning and mobile technologies in the development of digital biomarkers. Focusing on its application in the analysis of human movements, behaviors, and behavioral phenotypes, the course curriculum will encompass the fundamentals of human movement analysis, mobile and wearable sensing technologies to support remote human movement monitoring, fundamentals of signal processing techniques, and state-of-the-art machine learning techniques, all with the overarching goal of developing a reliable, responsive, and valid digital biomarker for motor deficits. In addition, we will cover essential topics such as human subject study design (e.g., randomized controlled trials) and hypothesis testing (e.g., t-test, ANOVA, correlation test, etc.). These skills are crucial for their application within the realm of clinical sciences, especially when it comes to assessing the effectiveness of emerging healthcare and wellness technologies. This course contains lectures, assignments, a final project, paper presentations, and critical discussions.

Open to graduate Computer Science students only. THERE ARE NO FORMAL PREREQUISITES FOR GRADUATE STUDENTS, BUT INFORMALLY, STUDENTS SHOULD BE FAMILIAR WITH STATISTICS AND MACHINE LEARNING. KNOWLEDGE OF HEALTH DATA OR MEDICINE IS NOT A PREREQUISITE; THIS COURSE IS DESIGNED TO INTRODUCE THE CONCEPTS OF HEALTH AND MEDICAL DATA. SEATS SAVED FOR INCOMING GRADUATE STUDENT REGISTRATION. STUDENTS NEEDING SPECIAL PERMISSION MUST REQUEST OVERRIDES VIA THE ON-LINE FORM: https://www.cics.umass.edu/academics/course-overrides