In this course students will examine the function of the nervous system with particular focus on mechanisms at work in the brain. The course will link current advances in cell, molecular and developmental physiology research in the context of neuronal functional mechanisms. Topics may include neurotransmitter function and regulation, brain area function, integrative intracellular signaling pathways, neuroendocrine control. Advanced topics may include the correlation of ion channel properties and synaptic transmission with physiological functions such as learning and memory, circuits involved in behavior, and the organizational principles for the development of functional neural networks at synaptic and cellular levels. Along with regular discussion participation and problem solving, students will prepare papers and lead discussions on their own chosen topics. This course is particularly appropriate for students interested in behavioral mechanisms, neurophysiology, psychology, and neuroendocrinology. This is a course in the Culture, Brain and Development Program.