Chemistry 339 - Org. Chem/Biol. Pathways
Spring
2017
01
4.00
Darren Hamilton
TH 01:15PM-04:05PM
Mount Holyoke College
98575
Kendade 203
hamilton@mtholyoke.edu
This course explores the underlying organic chemistry of biological pathways and thereby seeks to build a framework for understanding biological transformations from the perspective of mechanistic organic chemistry. Beginning with common biological mechanisms, and drawing parallels with their sophomore organic chemistry counterparts, a broad overview will be constructed of the pathways by which the key classes of biological molecules--lipids, carbohydrates, amino acids, nucleotides--are manufactured, modified, and consumed. Several specific biosyntheses will also be dissected from a mechanistic perspective. These case studies will include antibiotics, an alkaloid, and heme.
Prereq: CHEM-302.