Biological Sciences 321VX - Advanced Topics in Biological Sciences: 'Outsmarting Pathogens'

Smallpox, a disfiguring infection called "one of the most devastating diseases known to humanity" by the World Health Organization, was eradicated from the planet through immunization. Polio paralyzed 350,000 children a year until immunization reduced infection by 99%. Why have we succeeded in immunizing against these pathogens but not HIV or the common cold? Students in this seminar will discuss primary literature in immunology, microbiology, and epidemiology to learn how vaccines outsmart pathogens. Study of biological mechanisms will be complemented with exploration of the socioeconomic factors that influence vaccine development and usage. Students' independent research will connect their interests and current events to course concepts.

Two 200-level core courses in Biological Sciences, at least one of which must be BIOL-210 and/or BIOL-220. A student who has taken both BIOL-210 and BIOL-220 will be especially well prepared for this course. The 200-level core courses in Biological Sciences are BIOL-210, BIOL-220, BIOL-223, BIOL-224, BIOL-226, BIOL-227, and BIOL-241.