Students in this course achieve a basic knowledge of genetics, genomics and evolution. Principles to be covered include Central Dogma, genetics and genomics, molecular techniques, eukaryotic cell cycle, eukaryotic genomics, transmission genetics, population genetics, speciation and macroevolution. These principles will be illustrated using four central themes: (1) HIV and AIDS, (2) the making of a fly, (3) a matter of taste, (4) Origin of Species. In addition to lectures, each student participates in discussion sections that will focus on reading primary literature and mastering genetics problems. Laboratory (BIO 153) is recommended but not required.