Biology 397MH - Cellular&Molecular Biology Lab
Spring
2023
01
3.00
Jeffrey Laney
M F 1:25PM 4:25PM
UMass Amherst
59006
Integrated Sci Bldg 264
jlaney@umass.edu
This course is a hands-on project-based laboratory that focuses on the molecular and cellular analysis of mutations in the tumor suppressor gene p53, which is mutated in ~50% of cancerous human tumors. Students learn and apply different techniques of molecular cell biology to determine what, if any, functional defects are caused by different p53 mutations that have been identified previously in patient tumor samples. Emphasis will be placed on modeling how practicing scientists think and dissect such a biological problem, through the analysis of student-generated scientific data and the interpretation of such original experimental results.
This course is open to BIOLOGY majors only. CHEM 261 & BIOLOGY 283/285 Additional fees are associated with this section.