This course will introduce methods that are used to analyze compounds of biological importance. Such methods include both analytical techniques that are used to measure biomolecules and techniques that use biological processes for analyte detection. The course will discuss basic analytical theories and stay current by incorporating frequent examples of emerging bioanalytical techniques.

A course for first and second year graduate students focusing on protein and nucleic acid structure and function. Topics include: physical basis for structures, tools used in structure determination such as x-ray crystallography, NMR, and circular dichroism as well as structure prediction, visualization and design. Prerequisites: One full year of undergraduate organic chemistry.

Not available at this time

Introduction to quantum mechanics and its application to chemical problems; electronic structure of atoms and molecules, molecular orbital theory, chemical bonding, potential energy surfaces, and molecular spectroscopy. Prerequisite: CHEM 476 or equivalent .

Modern techniques for identification and structural analysis of organic compounds. Emphasis on the interpretation of spectra. Optional lab sections with opportunities to use spectroscopic facilities in the department, and to use spectroscopic techniques and procedures, such as nuclear-nuclear decoupling or 2-D NMR experiments (DEPT, COSY), spectral simulation and prediction, standard sample preparation methods. Completion of a two-semester physical chemistry course prior to enrollment strongly recommended.

Modern techniques for identification and structural analysis of organic compounds. Emphasis on the interpretation of spectra. Optional lab sections with opportunities to use spectroscopic facilities in the department, and to use spectroscopic techniques and procedures, such as nuclear-nuclear decoupling or 2-D NMR experiments (DEPT, COSY), spectral simulation and prediction, standard sample preparation methods. Completion of a two-semester physical chemistry course prior to enrollment strongly recommended.

Mechanisms of some important organic reactions. Topics covered may include application of qualitative molecular orbital theory to pericyclic reactions, free radical chemistry, photochemistry, heterocyclic systems, cationic and anionic reactions.

Basic atomic structure concepts; stereochemical principles and bonding models applied to main group and transition metal compounds and to the structure of solids. Includes elementary molecular orbital and ligand field theory, and kinetics and reaction mechanisms of d-block complexes. Descriptions of metal-metal bonded and organometallic systems. Structure and bonding principles applied to catalytic and biological system reactivity. Prerequisites: CHEM 241/341, 476.

Theory and practical application of modern instrumental methods for chemical analyses. Atomic and molecular spectroscopy, electroanalytical chemistry, chromatography and mass spectrometry. Applications to real analytical problems. Satisfies the Integrative Experience requirement for BA-Chem and BS-Chem majors.

Theory and practical application of modern instrumental methods for chemical analyses. Atomic and molecular spectroscopy, electroanalytical chemistry, chromatography and mass spectrometry. Applications to real analytical problems. Satisfies the Integrative Experience requirement for BA-Chem and BS-Chem majors.