This course introduces students to the field of biomedical microfluidics and biochips. It covers the fundamentals of microfluidic phenomena and microfabrication. The course also includes the design of microfluidic components and some biomedical applications of microfluidic systems.

This course is intended to serve as an introduction to bioimaging and its applications to medical fields. In this course, the fundamental physical principles behind the four primary medical imaging modalities (X-ray, magnetic resonance imaging, ultrasound, and nuclear imaging) will be introduced. In addition, the underlying image reconstruction algorithms will be described. Introduction of each imaging modality will also include the clinical interpretation of images it produces.

This course covers the breadth of drug delivery, from systemically delivered nanoparticles to local drug releasing systems. The course will consider the pharmaceutics of drugs and their disease target, and describe how to engineer drug delivery systems for these scenarios. Mathematical models, clinical examples, industry trends, and emerging research topics will be covered throughout the course.

This course provides an overview of the clinical diagnosis and contemporary treatment of major musculoskeletal disorders. The pathophysiology, epidemiology, and anatomy of the affected biological systems are covered. Students will develop an understanding of the challenges faced by clinicians, research scientists, and medical device manufacturing engineers. We will explore novel therapeutic approaches that integrate engineering and medicine to restore or improve function. Topics will include orthopedic trauma, sports injury, osteoporosis, and osteoarthritis.

Material science and mechanical engineering approaches are used to explore the structure-function relationships of natural biomaterials. Principles that govern mechanical behavior are used to discuss design approaches for synthetic bio-inspired and biomimetic materials. The main focus is on structure/function relationships of materials. There is also emphasis on mechanical design and function, with some discussion of cellular interactions.

The Commonwealth Honors College thesis or project is intended to provide students with the opportunity to work closely with faculty members to define and carry out in-depth research or creative endeavors. It provides excellent preparation for students who intend to continue their education through graduate study or begin their professional careers. The student works closely with their 499Y Honors Research sponsor to pursue research on a topic or question of special interest to them in preparation for writing a 499T Honors Thesis or completing a 499P Honors Project.

Honors Thesis expectations are high. The intended end-product is a traditional research manuscript with accompanying artifact(s), all theses: - are 6 credits or more of sustained research on a single topic, typically conducted over two semesters. - begin with creative inquiry and systematic research. - include documentation of substantive scholarly endeavor. - culminate in an oral defense or other form of public presentation. Students registering for an Honors Thesis following Honors Research (499Y) must have the approval of their faculty committee.

Honors Project expectations are high. The intended end-product is a traditional project manuscript with accompanying artifact(s), all projects: - are 6 credits or more of sustained research on a single topic, typically conducted over two semesters. - begin with creative inquiry and systematic research. - include documentation of substantive scholarly endeavor. - culminate in an oral defense or other form of public presentation. Students registering for an Honors Project following Honors Research (499Y) must have the approval of their faculty committee.

This course is intended to provide an introduction to dynamic mathematical modeling of cellular processes. The emphasis is on using computational tools to investigate models of cellular phenomena. Throughout the semester, students will develop skills to construct and analyze models of cellular networks, including: metabolic networks, signal transduction pathways, gene regulatory networks, and electrophysiology.