Description not available at this time

Description not available at this time

Not available at this time

This course will survey the current picture in pharmaceutical research, including how targets are selected, how the rational and combinatorial methods are harnessed, as well as how the industry is evolving in the post-genomic era. The instructors will provide background and introduce various topics, which will be discussed by a series of invited lecturers who are active in drug design and discovery. Prerequisites: One BIOCHEM class and one year of Organic Chemistry required.

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The application of chemical principles to modern materials discovery, design, and characterization will be discussed. Topics covered will include inorganic solids, nanoscale materials, polymers, inorganic-organic hybrid materials, and biological materials, with specific focus on how the atomic-level chemistries dictate material properties across various length scales. Aspects of materials chemistry with regard to scalability and sustainability will also be covered.

This course describes how the principles and techniques of organic chemistry, analytical chemistry, and physical chemistry can be used to study proteins, nucleic acids, and sugars. Methods for their synthesis, purification, and chemical manipulations will be discussed, focusing on the application of chemical approaches to studying biological questions. For each topic, appropriate bioanalytical techniques will be emphasized.

This class is focused on computational and mathematical problems in chemistry using modern symbolic computational tools. Using the software platform Mathematica (free to UMass students via site license), we will develop tools for data visualization and manipulation, and statistical methods in chemistry. In addition, we will explore aspects differential equation solving and visualization of solutions. Finally, we will explore elements of linear algebra, linear transformations, and group theory as applied to chemical systems.

Short review of thermodynamics. Introduction to statistical thermodynamics and its application to chemical problems. Statistical mechanical basis of thermodynamic behavior, e.g., entropy and attainment of equilibrium, and derivation of thermodynamic properties from basic microscopic description of molecules and solids, via quantum mechanics. Other topics may include gas imperfections, theory of liquids, adsorption, and molecular simulations.

The Commonwealth Honors College thesis or project is intended to provide students with the opportunity to work closely with faculty members to define and carry out in-depth research or creative endeavors. It provides excellent preparation for students who intend to continue their education through graduate study or begin their professional careers. The student works closely with their 499Y Honors Research sponsor to pursue research on a topic or question of special interest to them in preparation for writing a 499T Honors Thesis or completing a 499P Honors Project.