An introduction to the molecular and cellular processes common to life with an emphasis on control of energy and information flow. Central themes include metabolism, macromolecular function, and the genetic basis of cellular function. We examine how membranes work to establish the internal composition of cells; how the structure of proteins including enzymes affects protein function; how energy is captured, stored and utilized by cells; and how cells communicate, move and divide.

This course explores the biological mechanisms underlying infectious disease, as well as the challenges associated with fighting their emergence and spread. We will begin by learning about diseases of global health importance, such as HIV/AIDS and cholera, to introduce strategies that pathogens have evolved that ensure their persistence. We will investigate their fundamental biology, and interpret patterns of evolutionary divergence that aid in understanding patterns of transmission.

This course explores the biological mechanisms underlying infectious disease, as well as the challenges associated with fighting their emergence and spread. We will begin by learning about diseases of global health importance, such as HIV/AIDS and cholera, to introduce strategies that pathogens have evolved that ensure their persistence. We will investigate their fundamental biology, and interpret patterns of evolutionary divergence that aid in understanding patterns of transmission.

Independent reading course.

Fall and spring semesters. The Department.

(Offered as PHYS 400, BIOL 400, BCBP 400, and CHEM 400) How do the physical laws that dominate our lives change at the small length and energy scales of individual molecules? What design principles break down at the sub-cellular level and what new chemistry and physics becomes important? We will answer these questions by looking at bio-molecules, cellular substructures, and control mechanisms that work effectively in the microscopic world. How can we understand both the static and dynamic shape of proteins using the laws of thermodynamics and kinetics?