This course is an in-depth examination of DNA and RNA structures and how these structures support their respective functions during replication, transcription, and translation of the genetic material. Emphasis is on the detailed mechanisms associated with each step of gene expression. Discussions incorporate many recent advances brought about by recombinant DNA technology.

This course looks at the scientific content and intellectual context of Darwin's theory of evolution - his facts, metaphors, hypotheses, and philosophical assumptions. Readings from Darwin and his sources, and examination of the organisms he studied. A background in eighteenth- and nineteenth-century history or whole organism biology is recommended.

We will study the structure, function and evolution of the diversity of structures that allow vertebrates, including humans, to perform basic functions. We will connect these functions with day-to-day challenges for vertebrates, and we will discuss functional disruption such as disease and trauma. In lab, we will dissect fresh-frozen and formaline-preserved vertebrates. A willingness to work with such preserved material is critical to success in class. Students are expected to work in groups during class time, as well as read the required chapters before class.

What is regenerative medicine? What is the science that drives new medical therapies using stem cells? We will study the biology of adult, embryonic, and induced pluripotent stem cells, as well as the legal, ethical, and moral implications of using these cells in medical therapies. Each member of the class will participate in a staged debate on these issues for an introductory biology class.