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This course will survey the current picture in pharmaceutical research, including how targets are selected, how the rational and combinatorial methods are harnessed, as well as how the industry is evolving in the post-genomic era. The instructors will provide background and introduce various topics, which will be discussed by a series of invited lecturers who are active in drug design and discovery. Prerequisites: One BIOCHEM class and one year of Organic Chemistry required.

Discussion, oral presentations, problem solving, and reading of current literature pertinent to research interests of one or more faculty. For chemistry graduate students doing research.

A continuation of CHEM 265. Primary focus on reactions of the principal functional groups, and synthetic transformations between functional groups, including multi-reaction synthetic sequences. Includes some basic introduction to more complex organic systems such as carbohydrates, peptides, nucleic acids.

A one-semester introduction to chemistry of organic compounds: alkanes, alkenes, alkynes, aromatic compounds, alkyl halides, alcohols, ethers, aldehydes and ketones, carboxylic acids and their derivatives, phenols, amines, fats, amino acids, carbohydrates. Emphasizes nomenclature, structure, synthesis, stereochemistry, mechanisms of organic reactions. Prerequisite: CHEM 110 or 111 or equivalent.

Introduction to the macromolecules and networks of reactions of living cells, with emphasis on underlying chemical principles. Topics include structure of proteins and nucleic acids, mechanisms of enzyme catalysis, metabloic reaction networks, transfer of genetic information, and recombinant DNA technology.

For third year students. Does not satisfy the B.S. independent research project requirement. Experimental or theoretical study that may involve lab or library work or a combination. Work supervised by faculty sponsor who determines direction of project, nature of reports required, and grade and credit awarded. 3-4 hrs lab work per week per 1 unit is expected. This course cannot substitute for CHEM 388 or CHEM 499Y/T.

Discussion, oral presentations, problem solving, and reading of current literature pertinent to research interests of one or more faculty. For chemistry graduate students doing research.

Discussion, oral presentations, problem solving, and reading of current literature pertinent to research interests of one or more faculty. For chemistry graduate students doing research.

Introduction to the laws controlling equilibrium and kinetic properties of macroscopic chemical systems, using thermodynamics and statistical mechanics. Prerequisites: CHEM 475