The immune system protects the sterile interior of our bodies from the vast diversity of microbes in the outside world, adapting and improving from each encounter. How does it achieve this remarkable feat? This course will investigate the cells, organs, and biochemical signals that comprise innate and adaptive immune systems, as well as how they interact to identify and remove foreign pathogens. Emphasis will be placed on the human immune response to infectious diseases, with examples from clinical case studies and experimental models.

This course is an in-depth examination of DNA and RNA structures and how these structures support their respective functions during replication, transcription, and translation of the genetic material. Emphasis is on the detailed mechanisms associated with each step of gene expression. Discussions incorporate many recent advances brought about by recombinant DNA technology.

This course looks at the scientific content and intellectual context of Darwin's theory of evolution - his facts, metaphors, hypotheses, and philosophical assumptions. Readings from Darwin and his sources, and examination of the organisms he studied. A background in eighteenth- and nineteenth-century history or whole organism biology is recommended.

We will study the structure, function and evolution of the diversity of structures that allow vertebrates to perform basic functions such as locomotion. We will connect the functions with day-to-day challenges for vertebrates including humans, and we will discuss functional disruption such as disease and trauma. In lab we will dissect fresh-frozen and formaline-preserved vertebrates. A willingness to work with such preserved material is critical to success in class. Students are expected to work in groups during class time, as well as read the required chapters before class.