Emphasis on structure/function relationships, acquisition and transport of metal ions, electron transport proteins, respiratory proteins, redox proteins and enzymes, metalloenzymes with nonredox roles, medical aspects and spectroscopic methods for structure/function determination. Prerequisites: CHEM 546, BIOCHEM 523.

This course will present proteins, nucleic acids, and oligosaccharides from the perspective of organic chemistry. Methods for their synthesis, purification, and chemical manipulations will be discussed, focusing on the application of chemical approaches to studying biological questions. For each topic, appropriate bioanalytical techniques will be emphasized.

Description not available at this time

Not available at this time

Microwave, infrared, Raman, visible and ultra-violet spectra and structure. Molecular geometry from rotational spectra, normal coordinate analysis, anharmonicity and dissociation, hindered rotors, crystals, intensities and charge flux, vibrational dichroism, non-linear inelastic light scattering. Prerequisite: CHEM 476 or equivalent.

An overview of physical chemistry (thermodynamics, kinetics, statistical and quantum mechanics, and spectroscopy) emphasizing applications to biology including macromolecule structure and stability, ligand binding, enzyme catalysis, and membrance structure and transport.

Experimental organic chemistry with emphasis on underlying physical principles. Separation and purification, synthesis, analysis, and identification of organic compounds, including spectroscopy. Microscale work predominates. Emphasis on safe laboratory practices and proper disposal of wastes. Prerequisite or co-requisite: CHEM 262 or 266.

Description not available at this time

An overview of physical chemistry (thermodynamics, kinetics, statistical and quantum mechanics, and spectroscopy) emphasizing applications to biology including macromolecule structure and stability, ligand binding, enzyme catalysis, and membrance structure and transport.