The origin and maintenance of sexual reproduction stands as one of the great mysteries of evolutionary biology.  This seminar will explore the nature of sex and sexual reproduction across organisms, consider hypotheses for its origin and maintenance, and study its diverse consequences in populations.  Readings will incorporate articles from the primary literature and topics for consideration include the molecular machinery and origin of meiosis, variation in sex determination mechanisms (including the evolution of sex chromosomes), sex ratio evolution, mating system variation, sex

(Offered as CHEM 330 and BIOL 330.) What are the molecular underpinnings of processes central to life?  We will explore the chemical and structural properties of biological molecules and learn the logic used by the cell to build complex structures from a few basic raw materials. Some of these complex structures have evolved to catalyze chemical reactions with enormous degree of selectivity and specificity, and we seek to discover these enzymatic strategies.

(Offered as BIOL 301 and NEUR 301.)  An analysis of the molecules and molecular mechanisms underlying nervous system function, development, and disease.  We will explore the proteins that contribute to the unique structure and function of neurons, including an in-depth analysis of synaptic communication and the molecular processes that modify synapses.  We will also study the molecular mechanisms that control brain development, from neurogenesis, neurite growth and synaptogenesis to cell death and degeneration.

Independent reading or research courses. Full course as arranged. Does not normally count toward the major.

Fall and spring semesters.