Recently, the development of novel technologies for probing neurobiological questions has proceeded at a dizzying pace. This course focuses on three broad fields in neurotechnology: optical methods for examining neural activity and structures, innovations in electrophysiology, and mind-machine interfaces. Specific topics may include: optogenetics, 2-photon microscopy, 'brainbow' imaging, methods for single ion channel recording, and neuroprosthetics. Presentation, discussion, and critique of research articles will form the core of the course.