Important synthetic reactions, with emphasis on problems which may arise during organic synthesis. Develops students' ability to propose own syntheses of complex molecules. Prerequisite: CHEM 551 or consent of instructor.
Important synthetic reactions, with emphasis on problems which may arise during organic synthesis. Develops students' ability to propose own syntheses of complex molecules. Prerequisite: CHEM 551 or consent of instructor.
This course will survey the current picture in pharmaceutical research, including how targets are selected, how the rational and combinatorial methods are harnessed, as well as how the industry is evolving in the post-genomic era. The instructors will provide background and introduce various topics, which will be discussed by a series of invited lecturers who are active in drug design and discovery. Prerequisites: One BIOCHEM class and one year of Organic Chemistry required.
Application of principles of spectroscopy to structural aspects of inorganic substances. Infrared and Raman, nuclear magnetic resonance, electron paramagnetic resonance, nuclear quadrupole resonance, Mossbauer spectroscopy, photoelectron spectroscopy, and X-ray crystallography. Prerequisite: CHEM 546 or equivalent.
Short review of thermodynamics. Introduction to statistical thermodynamics and its application to chemical problems. Statistical mechanical basis of thermodynamic behavior, e.g., entropy and attainment of equilibrium, and derivation of thermodynamic properties from basic microscopic description of molecules and solids, via quantum mechanics. Other topics may include gas imperfections, theory of liquids, adsorption, and molecular simulations.