Moving from single genes to whole genomes, this course will focus on the molecular basis of biological inheritance. Major topics are Mendelian genetics, epigenetics, genomics, and bioinformatics. The course will begin with a review of fundamental concepts in Mendelian inheritance, including chromosome segregation, independent assortment, dominant and recessive alleles, and genetic variation. Epigenetics ? including hetero- and euchromatin and DNA methylation ? will be discussed in relation to chromosome behavior and gene expression.